My most comfortable knitting spot is the big comfy chair in the living room, with the footrest raised, so the back is ever so slightly reclined. As close to the "zero gee" position as I can get with normal living room furniture. :-) Knitting in bed always ends up with something cramped and something else falling asleep.

It's easier to knit sitting up in a comfortable armchair with a tall back than in bed propped up on inadequate pillows. For me, anyway.

Even easier sitting in a rocking chair with low arms just at elbow height.